The glycolytic enzyme PGAM1 functions as a metabolic–autophagy checkpoint to coordinate growth and stress tolerance 2026-08-04 Endothelial deletion of the neddylation E2 enzyme UBE2M inhibits tumor growth by promoting non-productive angiogenesis 2026-08-04 Atypical signaling, ligand recognition and selective agonist discovery of complement receptor C5aR2 2026-07-06 SPP1+ Macrophages Facilitate the Differentiation and Maturation of Regulatory T Cells in Tumor-Draining Lymph Nodes of Colorectal Cancer 2026-06-15 Targeting Coupling of Type H-like Vessels and Cell Fate Transition to Delay Soft Tissue Aging 2026-06-15 Cryo-EM structures of Drosophila OR67d–Orco complexes reveal insect pheromone sensing mechanism 2026-06-15 Localized Depletion of Macrophages by Abdominal Cavity Retention Nanoparticles as a Potential Therapy for Peritoneal Metastasis 2026-06-15 A cytosolic IF1 reporter enables real-time visualization of severe mitochondrial membrane damage 2026-06-05 Pre-existing anti-polyethylene glycol antibodies in pregnant women and newborns 2026-06-05 Exercise preserves β-cell function in type 2 diabetes by reshaping intra-islet macrophage-β-cell crosstalk 2026-05-27 Intrinsic bias of the genetic code shapes the folding and stability landscapes of microproteins 2026-05-22 ANXA11 suppression restores muscular function in the mdx mouse model of Duchenne muscular dystrophy (DMD) 2026-05-19 Creating highly active fluoroacetate dehalogenases via gate-based synergetic chain design 2026-05-19 Stabilizing MARCH7 as a ferro-guardian against ferroptosis 2026-04-29 Dynamic Monomer-Dimer Transition in Ligand-induced Apelin Receptor Activation 2026-04-15 Polyglutamine homorepeat regulates Runx2 condensation and cellular localization in a KPNA3-dependent manner 2026-04-09 SPTEdU-seq enables parallel optics-free newborn cell tracking and spatial total transcriptional dynamics in intact microenvironments 2026-04-09 An Epigenetic Switch for Sex-Specific Brain Resilience in Stroke: Targeting HDAC2 to Amplify Endogenous Oxytocin Signaling 2026-04-07 ATP13A2 restrains macrophage NLRP3 inflammasome activation to repress neurodegeneration via modulating mitochondrial homeostasis 2026-03-20 Fine-tuning ERK activity enables proliferation-differentiation balance during lineage specification of human embryonic stem cells 2026-03-19 
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